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Projects


  • Alternative Preclinical Models of Enteric Pathogen Infection (APMEP)

    APMEP is a $40-million NIH/NIAID IDIQ contract with the goal to develop alternative preclinical models of enteric pathogens. Through task orders, the contract establishes collaborations between NIMML and biotech and biopharma companies to accelerate the development of novel therapeutics, vaccines and diagnostics for enteric infections.


  • Modeling Infectious Disease Kinetics (MIDK-cWMD)

    MIDK is a $1.7-million DTRA grant that aims to leverage the power of computational modeling and advanced machine learning methods to model infectious disease kinetics. The ultimate goal of the project is to accelerate the development of effective countermeasures for people exposed to harmful pathogens or their toxins.


  • Modeling Immunity to Enteric Pathogens (MIEP)

    MIEP is a $12-million NIAID-funded program at the interface of advanced computational modeling and preclinical, translational and clinical research. MIEP is focused on the development and dissemination of computational models and tools for the studying immunoregulatory mechanisms underlying mucosal immune responses to enteric pathogens.

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  • Clinical
    • Clinical Development (Phase I-IV)
  • Pig Models
    • Neonatal pig model
    • Inflammatory bowel disease
    • Novel Pig Model of H. pylori
  • Media & Press Kit
    • Mission, Vision, Values
    • History
    • Quick Facts
    • Strategic Initiatives
  • ENISI Helicobacter Pylori Model
    • Sensitivity Analysis
    • Cell Movement Modeling
  • CDiff Computational Model Archive
    • Mucosal Immune Responses
    • PPAR γ and miRNA
  • EAEC Computational Model
    • Mucosal Immune Responses
    • T Cell Response
    • Epithelial Cell Responses
  • Macrophage Computational Model Archive
    • April 2012
    • Jan 2012
    • Oct 2011
  • COPASI Helicobacter Pylori Computational Model Archive
    • May 2012
    • April 2012
    • Jan 2012
    • Sep 2011
  • CD4+ T Cell Model Archive
    • Feb 2014
    • October 2012
    • August 2012
    • April 2012
    • Jan 2012
    • Sep 2011
    • June 2011
    • March 2011
  • Immunology
    • Helicobacter pylori
    • CD4+ T cell differentiation
    • Human Studies
    • Enteroaggregative E. coli
  • Animal Models
    • Type 2 Diabetes
    • Clostridium dificile infection
    • Influenza
    • Inflammatory bowel disease
    • Helicobacter pylori
    • Pig Models
    • Murine Models
  • Infectious Diseases
    • Helicobacter pylori
    • Clostridium difficile
    • Enteroaggregative E. coli
  • Immune Mediated Diseases
    • Novel IBD Interventions
  • Nutritional Immunology
    • Novel IBD Interventions
    • Phytochemicals
    • Dietary Lipids
    • Prebiotics and Probiotics
  • Drug Development
    • Host-targeted Therapeutics
    • Translational Medicine
  • Data
    • Modeling NLRX1 response to H.pylori
    • Modeling Clostridium difficile Immune Response
    • EAEC Zinc Deficiency
    • IL-21 in the Gastric Mucosa
    • Novel Pig Model
    • CD4+ T Cells
    • Modeling H. pylori Immune Response
    • Clostridium difficile
    • Enteroaggregative Escherichia coli
    • ENISI V0.9 in silico experiments
  • Computational Models
    • Inflammatory bowel disease
    • CD4+ T Cell Model
    • Host Responses to H. pylori
    • Host Responses to EAEC
    • Host Responses to C. difficile
    • Macrophages
  • Tools
    • CMS
    • CellDesigner
    • ENISI Suite
    • COPASI Suite
    • Galaxy
    • LabKey
    • RedCap
    • Intranet
    • CellPublisher
  • Projects
    • Alternate Preclinical Models Of Enteric Infection
    • Modeling Infectious Disease Kinetics (MIDK-cWMD)
  • Immunoinformatics
    • Computational Modeling
    • High Performance Computing
    • Transcriptomics
  • NIMML POLICIES
    • FCOI