MIEP team presented COPASI in MIB
COmplex PAthway SImulator: A Tool for Modeling Complex Immunological Systems New discoveries in immunology have triggered the production and development of novel, efficient and cost-effective tools to analyze complex immunological networks and target experimental approaches. The goal of the Center for Modeling Immunity for Enteric Pathogens (MIEP) is to support powerful software that can drive classical immunology in a targeted fashion by developing computational and mathematical intracellular pathways models controlling cellular differentiation, such as CD4+ T cell and macrophage differentiation, as well as models mimicking the immune cell distribution upon infection with Helicobacter pylori or Enteroaggregative E. coli. The Complex Pathway Simulator, COPASI, is a platform-independent, user-friendly software tool that allows easy access to powerful numerical methods for simulation and analysis of biochemical reaction networks and complex systems. The combination of COPASI and experimental data and immunological knowledge and novel discoveries allow multitask analysis and calculation of steady-states, time-courses and parameter estimations, among other functions. Stefan Hoops, Adria Carbo, Raquel Hontecillas, Katherine Wendelsdorf, Yongguo Mei, Sven Sahle, Ralph Gauges, Ursula Kummer, Pedro Mendes, Madhav Marathe, Stephen Eubank, and Josep Bassaganya-Riera